导师风采
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余晓丹
主任医师
博士生导师兼任专业学位导师
科室：发育行为儿科
专业：儿科学
911制品 发育行为儿科/儿保科主任
个人介绍
2004年毕业于上海第二医科大学获儿科学博士学位，师从沉晓明教授。长期致力于儿童营养性疾病、神经发育障碍性疾病的临床和科研工作，研究方向聚焦儿童营养与脑发育、食物过敏相关研究。主持4项国家重点专项和国家自然基金课题，以第一作者或通讯作者发表论文60多篇，其中厂颁滨收录30多篇，总影响因子140多分。入选“全国小儿内科专家国际论文学术影响力百强”；获第七届宋庆龄儿科医学成果奖；入选上海交通大学医学院“双百人计划”。任中国医师协会儿童肥胖学组副组长；中华医学会儿科学分会儿童保健学组秘书长；中国研究型医院学会儿童过敏性疾病学组组长；上海医学会儿科学分会儿童保健学组副组长。
研究方向
聚焦儿童营养与脑发育、食物过敏相关研究
余晓丹
招生信息
| 序号 | 专业 | 招生类型 | 招生人数 | 年份 |
| 1 | 儿科学 | 学术型博士 | 1 | 2022 |
| 2 | 儿科学 | 学术型博士 | 1 | 2024 |
余晓丹
科研项目
1. 上海市卫生健康委员会，老龄化和妇儿健康研究专项，2020YJZX0212，基于行为和营养的学龄前儿童ADHD医教结合干预模式的研究，2020/09-2023/08，40万元，在研，主持
2. 上海市卫生健康委员会，上海市公共卫生重点学科建设，上海交通大学-儿少卫生和妇幼卫生学，2020/07-2022/06，250万元，在研，分课题主持
3. 中国妇幼保健协会，妇儿健康临床标准与规范化项目，ZGFY-B-201904，婴幼儿维生素D微量血检测临床标准方法建立和规范，2020/01-2021/12，10万元，在研，主持
4. 上海交通大学医学院，高峰高原计划（第二轮），20152220，孕期维生素D添加规范标准研究，2019/01-2021/12，100万元，在研，主持
5. 上海儿童医学中心，儿科医疗联合体儿科分级诊疗临床技术及合作项目，基于行为和营养的学龄前儿童ADHD医教结合干预模式的研究婴幼儿食物过敏早期筛查及分级诊疗系统建立，2020/07-2021/07，15万元，在研，主持
6. 上海儿童医学中心，儿科医疗联合体儿科分级诊疗临床技术及合作项目，婴幼儿食物过敏早期筛查及分级诊疗系统建立，2019/07-2020/07，30万元，结题，主持
7. 国家自然科学基金委员会，面上项目，81773411，肠道菌群介导的维生素D影响婴幼儿食物过敏的前瞻性研究及作用机制，2018/01-2021/12,60万元，在研，主持
8.&苍产蝉辫;上海儿童医学中心，儿科医疗联合体儿科分级诊疗临床技术及合作项目，维生素顿影响肠道菌群及情绪行为的儿童早期发展促进项目，2018/06-2019/06，50万元，结题，主持
9. 上海交通大学,医工交叉重点项目, YG2017ZD15, 新型饲料添加剂致儿童肥胖的作用机制及干预研究，2018/01-2020/12，75万元，结题，主持
10. 上海卫生健康委员会，“儿科高级海外研修团队”项目，GDEK201708，早产儿适宜生长与神经发育、代谢性疾病，2017/06-2021/06，结题，主持
11. 上海市浦东新区科学技术委员会项目，PKJ2017-Y05，社区-医院联动探索婴儿喂养困难精准化干预效果和技术规范，2017/11-2020/11，结题，主持
12. 中华人民共和国科学技术部，国家重点研究计划重点专项，2016YFC1305204， 营养、运动对“糖尿病高危”青少年干预效果研究，2016/09-2020/12，125万元，结题，主持
13. 美国国立卫生研究院（NIH），探索/发展研究资助基金（R21），IR21ES026412-01，Maternal Methylmercury Exposure Through Rice Ingestion，Gut microbes and Offs pring Development，2016/02-2018/01，44万元，结题，中方负责人
14. 国家自然科学基金委员会，面上项目，81373004，孕期维生素D缺乏致儿童过敏疾病的出生队列和表观遗传机制研究， 2014/01-2017/12， 76万元，结题，主持
15. 中华人民共和国科学技术部，国家重点基础研究发展计划，2014CB943300，环境内分泌干扰物对女性生殖功能的影响及分子机制研究，2014/01-2018/12，90万元，结题，参加
16. 美国国立卫生研究院（NIH），学术研究加强基金（R15），IR15ES022409-01，Maternal Methylmercury Exposure Through Rice Ingestion and Offspring Development，2013/02-2015/12，50万元，结题，中方负责人
17. 上海市科学技术委员会，自然科学基金项目，11ZR1429800，锰影响幼鼠学习记忆的NMDA受体及细胞信号传导机制研究，2011/04-2014/03，10万元，结题，主持
18. 上海市科学技术委员会，医学引导类项目，114119a1600，儿童锌缺乏早期筛查指标的研究，2011/01-2013/06，10万元，结题，主持
19. 国家自然科学基金委员会，青年科学基金项目，30600496，锌指蛋白对发育期缺锌仔鼠学习记忆基因调控及功能干预研究，2007/01-2009/12，21万元，结题，主持
余晓丹
研究成果
1、 Wang X, Jiao X, Tian Y, Zhang J, Zhang Y, Li J, Yang F, Xu M, Yu X; Shanghai Birth Cohort Study. Associations between maternal vitamin D status during three trimesters and cord blood 25(OH)D concentrations in newborns: a prospective Shanghai birth cohort study. Eur J Nutr. 202; Epub ahead of print. doi: 10.1007/s00394-021-02528-w. Epub ahead of print. PMID: 33661376.
2、 Li J, Li J, Ma Y, Chen B, Wang X, Jiao X, Jin Y, Shen Z, Yuan T, Yu X; Urine concentrations of perfluoroalkyl acids in children and contributions of dietary factors: a cross-sectional study from Shanghai, China. Environ Sci Pollut Res Int. 2021;28(16):20440-20450. doi: 10.1007/s11356-020-12293-8.
3、Wang X, Jiao X, Xu M, Wang B, Li J, Yang F, Zhang L, Xu L, Yu X. Effects of circulating vitamin D concentrations on emotion, behavior and attention: A cross-sectional study in preschool children with follow-up behavior experiments in juvenile mice. J Affect Disord. 2020;275:290-298. doi: 10.1016/j.jad.2020.06.043.
4、 Jiao X, Yuan Y, Wang X, Li J, Liu B, Yuan T, Yu X. Development of a sensitive HPLC-MS/MS method for 25-hydroxyvitamin D2 and D3 measurement in capillary blood. J Clin Lab Anal. 2020;34(10):e23451. doi: 10.1002/jcla.23451.
5、Chen J, Zhao X, Cui L, He G, Wang X, Wang F, Duan S, He L, Li Q, Yu X, Zhang F, Xu M. Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders. Aging (Albany NY). 2020;12(9):8434-8458. doi: 10.18632/aging.103150.
6、Chen M, Guo WL, Li QY, Xu JX, Cao YJ, Liu B, Yu XD, Rao PF, Ni L, Lv XC. The protective mechanism of Lactobacillus plantarum FZU3013 against non-alcoholic fatty liver associated with hyperlipidemia in mice fed a high-fat diet. Food Funct. 2020;11(4):3316-3331. doi: 10.1039/c9fo03003d.
7、 Zeng F, Li T, Zhao H, Chen H, Yu X, Liu B. Effect of debranching and temperature-cycled crystallization on the physicochemical properties of kudzu (Pueraria lobata) resistant starch. Int J Biol Macromol. 2019;129:1148-1154. doi: 10.1016/j.ijbiomac.2019.01.028.
8、 Jiao X, Wang L, Wei Z, Liu B, Liu X, Yu X. Vitamin D deficiency during pregnancy affects the function of Th1/Th2 cells and methylation of IFN-γ gene in offspring rats. Immunol Lett. 2019;212:98-105. doi: 10.1016/j.imlet.2019.06.012.
9、hen W, Yang X, Wang B, Wang L, Yu X. The effects and possible mechanisms of triclosan on steroidogenesis in primary rat granulosa cells. Reprod Toxicol. 2019;83:28-37. doi: 10.1016/j.reprotox.2018.11.001.
10、 Wang B, Liu J, Liu B, Liu X, Yu X. Prenatal exposure to arsenic and neurobehavioral development of newborns in China. Environ Int. 2018;121(Pt 1):421-427. doi: 10.1016/j.envint.2018.09.031.
11、 Jiao X, Chen W, Zhang J, Wang W, Song J, Chen D, Zhu W, Shi Y, Yu X. Variant Alleles of the ESR1, PPARG, HMGA2, and MTHFR Genes Are Associated With Polycystic Ovary Syndrome Risk in a Chinese Population: A Case-Control Study. Front Endocrinol (Lausanne). 2018;9:504. doi: 10.3389/fendo.2018.00504.
12、 Chen W, Jiao X, Zhang J, Wang L, Yu X. Vitamin D deficiency and high serum IL-6 concentration as risk factors for tubal factor infertility in Chinese women. Nutrition. 2018;49:24-31. doi: 10.1016/j.nut.2017.11.016.
13、 Wang H, Yu XD, Huang LS, Chen Q, Ouyang FX, Wang X, Zhang J. Fetal vitamin D concentration and growth, adiposity and neurodevelopment during infancy. Eur J Clin Nutr. 2018;72(10):1396-1403. doi: 10.1038/s41430-017-0075-9.
14、 Lei X, Zhao D, Huang L, Luo Z, Zhang J, Yu X, Zhang Y. Childhood Health Outcomes in Term, Large-for-Gestational-Age Babies With Different Postnatal Growth Patterns. Am J Epidemiol. 2018;187(3):507-514. doi: 10.1093/aje/kwx271.
15、 Wang L, Fu H, Liu B, Liu X, Chen W, Yu X. The effect of postnatal manganese exposure on the NMDA receptor signaling pathway in rat hippocampus. J Biochem Mol Toxicol. 2017;31(12). doi: 10.1002/jbt.21969.
16、 Fu H, Chen W, Yu H, Wei Z, Yu X. The effects of preweaning manganese exposure on spatial learning ability and p-CaMKIIα level in the hippocampus. Neurotoxicology. 2016;52:98-103. doi: 10.1016/j.neuro.2015.11.013.
17、 Wei Z, Zhang J, Yu X. Maternal vitamin D status and childhood asthma, wheeze, and eczema: A systematic review and meta-analysis. Pediatr Allergy Immunol. 2016;27(6):612-9. doi: 10.1111/pai.12593.
18、 Yu X, Chen W, Wei Z, Ren T, Yang X, Yu X. Effects of maternal mild zinc deficiency and different ways of zinc supplementation for offspring on learning and memory. Food Nutr Res. 2016;60:29467. doi: 10.3402/fnr.v60.29467.
19、 Rothenberg SE, Yu X, Liu J, Biasini FJ, Hong C, Jiang X, Nong Y, Cheng Y, Korrick SA. Maternal methylmercury exposure through rice ingestion and offspring neurodevelopment: A prospective cohort study. Int J Hyg Environ Health. 2016;219(8):832-842. doi: 10.1016/j.ijheh.2016.07.014.
20、 Hong C, Yu X, Liu J, Cheng Y, Rothenberg SE. Low-level methylmercury exposure through rice ingestion in a cohort of pregnant mothers in rural China. Environ Res. 2016;150:519-527. doi: 10.1016/j.envres.2016.06.038.
21、 Yu X, Chen L, Wang C, Yang X, Gao Y, Tian Y. The role of cord blood BDNF in infant cognitive impairment induced by low-level prenatal manganese exposure: LW birth cohort, China. Chemosphere. 2016;163:446-451. doi: 10.1016/j.chemosphere.2016.07.095.
22、 Wei Z, Wang W, Zhang J, Zhang X, Jin L, Yu X. Urinary iodine level and its determinants in pregnant women of Shanghai, China. Br J Nutr. 2015;113(9):1427-32. doi: 10.1017/S0007114515000665.
23、 Yu XD, Zhang J, Yan CH, Shen XM. Prenatal exposure to manganese at environment relevant level and neonatal neurobehavioral development. Environ Res. 2014;133:232-8. doi: 10.1016/j.envres.2014.04.012.
24、 Yu X, Wang W, Wei Z, Ouyang F, Huang L, Wang X, Zhao Y, Zhang H, Zhang J. Vitamin D status and related factors in newborns in Shanghai, China. Nutrients. 2014;6(12):5600-10. doi: 10.3390/nu6125600.
25、 Li L, Zhou H, Yang X, Zhao L, Yu X. Relationships between 25-hydroxyvitamin D and nocturnal enuresis in five- to seven-year-old children. PLoS One. 2014;9(6):e99316. doi: 10.1371/journal.pone.0099316.
26、 Yang X, Bao Y, Fu H, Li L, Ren T, Yu X. Selenium protects neonates against neurotoxicity from prenatal exposure to manganese. PLoS One. 2014;9(1):e86611. doi: 10.1371/journal.pone.0086611.
27、Yu X, Zhang J, Yan C, Shen X. Relationships between serum 25-hydroxyvitamin D and quantitative ultrasound bone mineral density in 0-6 year old children. Bone. 2013;53(1):306-10. doi: 10.1016/j.bone.2012.12.012.
28、 Yu X, Cao L, Yu X. Elevated cord serum manganese level is associated with a neonatal high ponderal index. Environ Res. 2013;121:79-83. doi: 10.1016/j.envres.2012.11.002.
29、 Rothenberg SE, Yu X, Zhang Y. Prenatal methylmercury exposure through maternal rice ingestion: insights from a feasibility pilot in Guizhou Province, China. Environ Pollut. 2013;180:291-8. doi: 10.1016/j.envpol.2013.05.037.
30、 Yu X, Jin L, Zhang X, Yu X. Effects of maternal mild zinc deficiency and zinc supplementation in offspring on spatial memory and hippocampal neuronal ultrastructural changes. Nutrition. 2013;29(2):457-61. doi: 10.1016/j.nut.2012.09.002.
31、 Yu X, Ren T, Yu X. Disruption of calmodulin-dependent protein kinase II α/brain-derived neurotrophic factor (α-CaMKII/BDNF) signalling is associated with zinc deficiency-induced impairments in cognitive and synaptic plasticity. Br J Nutr. 2013;110(12):2194-200. doi: 10.1017/S0007114513001657.
32、 Yang X, Yu X, Fu H, Li L, Ren T. Different levels of prenatal zinc and selenium had different effects on neonatal neurobehavioral development. Neurotoxicology. 2013;37:35-9. doi: 10.1016/j.neuro.2013.04.001.
33、 Yu XD, Branch DW, Karumanchi SA, Zhang J. Preeclampsia and retinopathy of prematurity in preterm births. Pediatrics. 2012;130(1):e101-7. doi: 10.1542/peds.2011-3881.
34、 Yu XD, Shen XM, Xue MB, Yan CH. Vitamin D receptor gene polymorphism and bone mineral density in 0-6-year-old Han children. J Bone Miner Metab. 2011;29(1):54-61. doi: 10.1007/s00774-010-0190-3.
35、 Yu XD, Yan CH, Shen XM, Tian Y, Cao LL, Yu XG, Zhao L, Liu JX. Prenatal exposure to multiple toxic heavy metals and neonatal neurobehavioral development in Shanghai, China. Neurotoxicol Teratol. 2011;33(4):437-43. doi: 10.1016/j.ntt.2011.05.010.
